Jackson and april

Just in time for season 15 of "Grey's Anatomy," check out this ranking of the best 22 couples from the show's long history, from Callie and George to Derek and Meredith.

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Relive Dr. Jackson Avery and Dr. April Kepner’s most romantic 'Grey's Anatomy' moments ever before Jesse Williams exits the show — photos

So much has happened in the past 12 seasons of Grey's Anatomy. If you could change some major aspects of the show would you? Take this Grey's Anatomy themed, "would you rather" quiz to determine how you would have liked to see things pan out.