Homemade Gripe Water Recipe:Their are three primary ingredients in gripe water: chamomile, fennel, and ginger. Fennel has been used by herbalists and homeopaths for centuries to help with indigestion and as a gas-reliever. It also has some pain relieving properties. Ginger is a great herb for any problems in thr gastrointestinal tract, including nausea and gas. The third ingredient I use, chamomile, is great at reducing restlessness and insomnia and helps with irritability and anxiousness.