Regina Building One of the earliest structures made of reinforced concrete, a material introduced during the American colonial period. The original three-story building was designed by Andres Luna San Pedro. In the early 1930's it was bought by the De Leon family from the Roxas family and a fourth floor commissioned from architectFernando Ocampo. The building is one of Manila's architectural landmarks, and is an example of the Art Deco style. Together with the Perez-Samanillo.